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Asp79 makes a large, unfavorable contribution to the stability of RNase Sa

  • Saul R. Trevino
  • , Kuppan Gokulan
  • , Stephanie Newsom
  • , Richard L. Thurlkill
  • , Kevin L. Shaw
  • , Vladimir A. Mitkevich
  • , Alexander A. Makarov
  • , James C. Sacchettini
  • , J. Martin Scholtz
  • , C. Nick Pace
  • Texas A and M University
  • Department of Biochemistry and Biophysics, Texas A and M University
  • University of Texas Health Science Center
  • Grove City College
  • Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
  • University of Oslo

Research output: Contribution to journal › Article › peer-review

Original languageEnglish
Pages (from-to)967-978
Number of pages12
JournalJournal of Molecular Biology
Volume354
Issue number4
DOIs
StatePublished - Dec 9 2005
Externally publishedYes

ASJC Scopus Subject Areas

  • Biophysics
  • Structural Biology
  • Molecular Biology

Keywords

  • Buried carboxyl group
  • Hydrogen bonds
  • Ion pair
  • pK
  • Protein stability

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