Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase

Quanjie Li; Dongrong Yi; Xiaobo Lei; Jianyuan Zhao; Yongxin Zhang; Xiangling Cui; Xia Xiao; Tao Jiao; Xiaojing Dong; Xuesen Zhao; Hui Zeng; Chen Liang; Lili Ren; Fei Guo; Xiaoyu Li; Jianwei Wang; Shan Cen

doi:10.1016/j.apsb.2021.02.011

Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase

Quanjie Li
, Dongrong Yi
, Xiaobo Lei
, Jianyuan Zhao
, Yongxin Zhang
, Xiangling Cui
, Xia Xiao
, Tao Jiao
, Xiaojing Dong
, Xuesen Zhao
, Hui Zeng
, Chen Liang
, Lili Ren
, Fei Guo
, Xiaoyu Li
, Jianwei Wang
, Shan Cen

Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College
Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing Ditan Hospital Capital Medical University
Lady Davis Institute-Jewish General Hospital
Chinese Academy of Medical Sciences and Peking Union Medical College

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1555-1567
Number of pages	13
Journal	Acta Pharmaceutica Sinica B
Volume	11
Issue number	6
DOIs	https://doi.org/10.1016/j.apsb.2021.02.011
State	Published - Jun 2021
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus Subject Areas

General Pharmacology, Toxicology and Pharmaceutics

Keywords

Corilagin
Drug combinations
Non-nucleoside inhibitor
RdRp
SARS-CoV-2
Structure-based virtual screening
Viral replication

Access to Document

10.1016/j.apsb.2021.02.011

Cite this

@article{612c4be9c48a423ab08883ccfa404a94,

title = "Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase",

keywords = "Corilagin, Drug combinations, Non-nucleoside inhibitor, RdRp, SARS-CoV-2, Structure-based virtual screening, Viral replication",

author = "Quanjie Li and Dongrong Yi and Xiaobo Lei and Jianyuan Zhao and Yongxin Zhang and Xiangling Cui and Xia Xiao and Tao Jiao and Xiaojing Dong and Xuesen Zhao and Hui Zeng and Chen Liang and Lili Ren and Fei Guo and Xiaoyu Li and Jianwei Wang and Shan Cen",

note = "Publisher Copyright: {\textcopyright} 2021 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences",

year = "2021",

month = jun,

doi = "10.1016/j.apsb.2021.02.011",

language = "English",

volume = "11",

pages = "1555--1567",

journal = "Acta Pharmaceutica Sinica B",

issn = "2211-3835",

number = "6",

}

TY - JOUR

T1 - Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase

AU - Li, Quanjie

AU - Yi, Dongrong

AU - Lei, Xiaobo

AU - Zhao, Jianyuan

AU - Zhang, Yongxin

AU - Cui, Xiangling

AU - Xiao, Xia

AU - Jiao, Tao

AU - Dong, Xiaojing

AU - Zhao, Xuesen

AU - Zeng, Hui

AU - Liang, Chen

AU - Ren, Lili

AU - Guo, Fei

AU - Li, Xiaoyu

AU - Wang, Jianwei

AU - Cen, Shan

PY - 2021/6

Y1 - 2021/6

KW - Corilagin

KW - Drug combinations

KW - Non-nucleoside inhibitor

KW - RdRp

KW - SARS-CoV-2

KW - Structure-based virtual screening

KW - Viral replication

UR - https://www.scopus.com/pages/publications/85103687635

UR - https://www.scopus.com/pages/publications/85103687635#tab=citedBy

U2 - 10.1016/j.apsb.2021.02.011

DO - 10.1016/j.apsb.2021.02.011

M3 - Article

AN - SCOPUS:85103687635

SN - 2211-3835

VL - 11

SP - 1555

EP - 1567

JO - Acta Pharmaceutica Sinica B

JF - Acta Pharmaceutica Sinica B

IS - 6

ER -

Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase

UN SDGs

ASJC Scopus Subject Areas

Keywords

Access to Document

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