HIV-1 employs multiple mechanisms to resist Cas9/Single Guide RNA targeting the viral primer binding site

Zhen Wang; Wenzhou Wang; Ya Cheng Cui; Qinghua Pan; Weijun Zhu; Patrick Gendron; Fei Guo; Shan Cen; Michael Witcher; Chen Liang

doi:10.1128/JVI.01135-18

HIV-1 employs multiple mechanisms to resist Cas9/Single Guide RNA targeting the viral primer binding site

Zhen Wang
, Wenzhou Wang
, Ya Cheng Cui
, Qinghua Pan
, Weijun Zhu
, Patrick Gendron
, Fei Guo
, Shan Cen
, Michael Witcher
, Chen Liang

Lady Davis Institute-Jewish General Hospital
McGill University
Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
University of Montreal
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e01135
Journal	Journal of Virology
Volume	92
Issue number	20
DOIs	https://doi.org/10.1128/JVI.01135-18
State	Published - Oct 1 2018
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus Subject Areas

Microbiology
Immunology
Insect Science
Virology

Keywords

CRISPR-Cas9
Human immunodeficiency virus
Primer binding site

Access to Document

10.1128/JVI.01135-18

Cite this

@article{a4d38bbf26244e73882ee85a52c71c6b,

title = "HIV-1 employs multiple mechanisms to resist Cas9/Single Guide RNA targeting the viral primer binding site",

keywords = "CRISPR-Cas9, Human immunodeficiency virus, Primer binding site",

author = "Zhen Wang and Wenzhou Wang and Cui, \{Ya Cheng\} and Qinghua Pan and Weijun Zhu and Patrick Gendron and Fei Guo and Shan Cen and Michael Witcher and Chen Liang",

year = "2018",

month = oct,

day = "1",

doi = "10.1128/JVI.01135-18",

language = "English",

volume = "92",

journal = "Journal of Virology",

issn = "0022-538X",

number = "20",

}

TY - JOUR

T1 - HIV-1 employs multiple mechanisms to resist Cas9/Single Guide RNA targeting the viral primer binding site

AU - Wang, Zhen

AU - Wang, Wenzhou

AU - Cui, Ya Cheng

AU - Pan, Qinghua

AU - Zhu, Weijun

AU - Gendron, Patrick

AU - Guo, Fei

AU - Cen, Shan

AU - Witcher, Michael

AU - Liang, Chen

PY - 2018/10/1

Y1 - 2018/10/1

KW - CRISPR-Cas9

KW - Human immunodeficiency virus

KW - Primer binding site

UR - https://www.scopus.com/pages/publications/85054753768

UR - https://www.scopus.com/pages/publications/85054753768#tab=citedBy

U2 - 10.1128/JVI.01135-18

DO - 10.1128/JVI.01135-18

M3 - Article

C2 - 30068653

AN - SCOPUS:85054753768

SN - 0022-538X

VL - 92

JO - Journal of Virology

JF - Journal of Virology

IS - 20

M1 - e01135

ER -

HIV-1 employs multiple mechanisms to resist Cas9/Single Guide RNA targeting the viral primer binding site

UN SDGs

ASJC Scopus Subject Areas

Keywords

Access to Document

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