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MOV10 recruits DCP2 to decap human LINE-1 RNA by forming large cytoplasmic granules with phase separation properties

  • Qian Liu
  • , Dongrong Yi
  • , Jiwei Ding
  • , Yang Mao
  • , Shujie Wang
  • , Ling Ma
  • , Quanjie Li
  • , Jing Wang
  • , Yongxin Zhang
  • , Jianyuan Zhao
  • , Saisai Guo
  • , Zhenlong Liu
  • , Fei Guo
  • , Dongbing Zhao
  • , Chen Liang
  • , Xiaoyu Li
  • , Xiaozhong Peng
  • , Shan Cen
  • Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College
  • Lady Davis Institute-Jewish General Hospital
  • Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
  • Chinese Academy of Medical Sciences and Peking Union Medical School
  • Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article numbere56512
JournalEMBO Reports
Volume24
Issue number9
DOIs
StatePublished - Sep 6 2023
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Molecular Biology
  • Genetics

Keywords

  • DCP2
  • LINE-1
  • MOV10
  • RNA decap
  • liquid–liquid phase separation

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