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The CREB Regulated Transcription Coactivator 2 Suppresses HIV-1 Transcription by Preventing RNA Pol II from Binding to HIV-1 LTR

  • Ling Ma
  • , Shumin Chen
  • , Zhen Wang
  • , Saisai Guo
  • , Jianyuan Zhao
  • , Dongrong Yi
  • , Quanjie Li
  • , Zhenlong Liu
  • , Fei Guo
  • , Xiaoyu Li
  • , Pingping Jia
  • , Jiwei Ding
  • , Chen Liang
  • , Shan Cen
  • Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College
  • Qingdao University
  • Lady Davis Institute-Jewish General Hospital
  • Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
  • Beijing Shijitan Hospital
  • Chinese Academy of Medical Sciences and Peking Union Medical College
  • Beijing Friendship Hospital, Capital Medical University

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)796-809
Number of pages14
JournalVirologica Sinica
Volume36
Issue number4
DOIs
StatePublished - Aug 2021
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

ASJC Scopus Subject Areas

  • Immunology
  • Molecular Medicine
  • Infectious Diseases
  • Virology

Keywords

  • CREB regulated transcription coactivator 2 (CRTC2)
  • Human immunodeficiency virus (HIV)
  • Infection
  • Latency
  • Long terminal repeat (LTR)
  • RNA polymerase II (RNA Pol II)
  • Viral transcription
  • Virology

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